Intestinal Necrosis due to Sodium Polystyrene Sulfonate (Kayexalate) in Sorbitol

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Sodium polystyrene sulfonate (Kayexalate) aspiration

In this short report we illustrate a case of extensive sodium polystyrene sulfonate (SPS) aspiration as an immediate cause of death in a terminally ill patient. SPS is a cation exchange resin utilized to decrease potassium levels in patients with renal failure. When administered rectally in conjunction with sorbitol, colonic necrosis and perforation have been documented. On the other hand, oral...

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Cation-exchange resins are used in the management of hyperkalemia, particularly in patients with end-stage renal disease. These resins were associated with gastrointestinal tract lesions, especially sodium polystyrene sulfonate (Kayexalate) mixed with sorbitol. We present a case of colonic necrosis after the administration of calcium polystyrene sulfonate (Kalimate) not suspended in sorbitol.

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ژورنال

عنوان ژورنال: Southern Medical Journal

سال: 2009

ISSN: 0038-4348

DOI: 10.1097/smj.0b013e31819e8978